Proving Evolution to Dennis Prager


Dennis Prager, the talk-show host behind the YouTube channel, "PragerU" posted a video showing how he has been duped into believing and promoting Intelligent Design "theory". I have already rebutted a number of his earlier videos, one where he said that atheism is irrational, another when he said the Ten Commandments were real and changed the world for the better, and again when he conflated left-wing politics with far-right fascism, making the blanket accusation that "the left" is an embodiment of evil and must be destroyed. Now, here is the video I made to rebut his most recent declaration of support for his anti-science position against evolutionary theory.

Here are the terms of my challenge: I can show that biological evolution is the truest, best explanation there is or ever was for the origin of our species, that it is the only explanation of biodiversity with either evidentiary support or scientific validity, while Intelligent Design does not even qualify as a theory. I will prove—even to your satisfaction—that evolution is indeed an inescapable fact of fossils, phylogeny and biology. I can do all of this within the course of a dozen mutual exchanges; (one post from me answered by one post from you) throughout which I will also correct whatever errors you currently hold which impede your understanding. I will start with the basics and you must confirm your comprehensive progress in order to advance to the next mutual exchange. Because this is an attempt to educate, it must be a Socratic interaction. So I must insist that you properly address every point or query, ignoring none. If you repeatedly ignore direct questions, your evasion will default this discussion, and I will be under no obligation to continue. I have to say that up-front because that is the way that everyone who has ever attempted this challenge has always failed, with the one notable exception of my wife, Lilandra.
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Where Do Complex Organisms Come From?

What are the REAL mechanisms of biodiversity, replacing macroevolution?

Based on evidence seen in biochemistry on a molecular level, we can now say affirmatively and conclusively, that Darwins theory of evolution by natural selection in regards of first degree speciation & macroevolutionary level has been falsified.

The real mechanisms that explain biodiversity and complex organismal architecture is preprogrammed instructional complex INFORMATION encoded in various genetic and epigenetic languages and communication by various signalling codes through various signalling networks

That brings us to the origin by an intelligent designer.

Pinpointing what REALLY defines body architecture, the orchestration of organism development, cell shape and body form and the mechanisms of adaptation and primary speciation, and exposing the correct explanation of biochemical mechanisms of biodiversity is the holy grail of biological sciences. Preprogrammed codified information and signalling replaces Darwin's theory and its various subsequent adaptations, extensions, and new proposals like the modern extended synthesis or the so-called " third way ". The true mechanism is " Biochemical systems programming and signalling", and special creation of species and/or kinds by an intelligent powerful creator. Long periods of time and gradual, evolutionary development is not possible, face the fact that cells and organisms work like gigantic interlocked machines and factory complexes, where in any case, if one tiny part is missing, nothing goes. Natural selection would not select for components of a complex system that would be useful only in the completion of that much larger system. No glycine amino acids, no pyrimidines, no DNA - no life. No Watson Crick base pair fine-tuning, no DNA - no life. No ribosomal mechanism for amino acid amide bondage, no proteins, no life. No nitrogenase enzymes to fix nitrogen in an energy demanding, triple bond breaking process, no ammonia, required to make amino acids - no nitrogen cycle - no advanced life. No chlorophylls, no absorption of light to start photosynthesis, no starch and glucose - cells will have no food supply to sustain complex organisms - no advanced life on earth. No rubisco, no fix of CO2, no hydrocarbons - no advanced life. No counterion in retinal, and rhodopsin could not receive visible light - and there would be no vision on earth by any organism.

1. The Gene regulation network orchestrates gene expression
2. Various signalling pathways generate Cell types and patterns
3. At least 23 Epigenetic Codes are multidimensional and perform various tasks essential to cell structure and development
4. Cell-Cell communication in various forms, especially important for animal development
5. Chromatin dance in the nucleus through extensile motors affect transcription and gene regulation
6. Post-transcriptional modifications (PTMs) of histones affect gene transcription
7. The DNA methylation code is like a barcode or marker, the methyl group indicates, for instance, which genes in the DNA are to be turned on.
8. Homeobox and Hox genes determine the shape of the body.
9. Noncoding DNA ( Junk DNA ) is transcribed into functional non-coding RNA molecules and switches protein-coding genes on or off.
10. Transposons and Retrotransposons regulate genes
11. Centrosomes play a central role in development
12. The precise arrangement of Cytoskeletal arrays provides critical structural information.
13. Membrane targets provide crucial information—spatial coordinates—for embryological development.
14. Ion Channels and Electromagnetic Fields influence the form of a developing organism
15. The Sugar Code forms information-rich structures which influence the arrangement of different cell types during embryological development.
16. Egg-polarity genes encode macromolecules deposited in the egg to organize the axes
17. Hormones are special chemical messengers for development

1. Biological sciences have come to discover in the last decades that major morphological innovation, development and body form are based on at least 16 different, but integrative mechanisms, the interplay of genes with the gene regulatory network, Trans and Retrotransposons, so-called Junk DNA, gene splicing and recombination, and at least two dozen epigenetic informational code systems, some, like the glycan ( sugar) code, far more complex than the genetic code, on the membrane - exterior side of cells, Post-transcriptional modifications (PTMs) of histones, hormones, Ion Channels and Electromagnetic Fields that are not specified by nuclear DNA, Membrane targets and patterns, Cytoskeletal arrays, Centrosomes, and inheritance by cell memory which is not defined through DNA sequences alone.

2. These varied mechanisms orchestrate gene expression, generate Cell types and patterns, perform various tasks essential to cell structure and development, are responsible for important tasks of organismal development, affect gene transcription, switch protein-coding genes on or off, determine the shape of the body, regulate genes, provide critical structural information and spatial coordinates for embryological development, influence the form of a developing organism and the arrangement of different cell types during embryological development, organize the axes, and act as chemical messengers for development

3. Neo-Darwinism and the Modern Synthesis have proposed traditionally a gene-centric view, a scientific metabiological proposal going back to Darwin's " On the origin of species ", where first natural selection was proposed as the mechanism of biodiversity, and later, gene variation defining how bodies are built and organized. Not even recently proposed alternatives, like the third way, neutral theory, inclusive fitness theory, Saltationism, Saltatory ontogeny, mutationism, Genetic drift, or combined theories, do full justice by taking into account all organizational physiological hierarchy and complexity which empirical science has come to discover.

4. Only a holistic view, namely structuralism and systems biology, take into account all influences that form cell form and size, body development and growth, providing adequate descriptions of the scientific evidence. The BIG ( umbrella ) contributor to explain organismal complexity is preprogrammed instructional complex INFORMATION encoded in various languages and communication through signalling through various signalling networks that act on a structural level, which are pre-instructed to respond to environmental cues, development, and nutrition demands, and they are apt to communicate, crosstalk, signal, regulate, govern, control, recruit, interpret, recognize, orchestrate, elaborate strategies, guide and so forth. All codes, blueprints, and languages are inventions by intelligence. Therefore, the genetic and epigenetic codes and signalling networks and the instructions to build cells and complex biological organisms were most likely created by an intelligent agency.