sophophilo
New Member
:roll:
problem for common ancestry?
problem for common ancestry?
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I asked a question... thats not illegal, isn't it?Aught3 said:Why did you post this topic? .
Than you may not be the most qualified for an answer to begin with...Josan said:I have no idea what you are talking about, maybe some more information or a source would be nice?
Like Josan said, it just seemed weird that you posted no info on what ORFans were, or what kind of answer you are looking for.sophophilo said:I asked a question... thats not illegal, isn't it?
Does the classification goes all the way there? I don't know I'm not a biologist.Aught3 said:^That sounds like common ancestry to me.
Aught3 said:Yeah biology, it's not as strict as math so many fluffy definitions.
Siew and Fischer (2003) said:Many ORFans may have been generated as the result of a number of possible evolutionary events, which may include horizontal transfer, rapid evolution and gene-loss. ORFans (and other ORFs) without selection pressure have been deleted throughout microbial deletion mechanisms, and thus, microbial genomes are kept at 'reasonable sizes' [43]. ORFans that have retained or acquired an important function are kept, thus creating new sequence families with a seed of a single ORFan.
Siew and Fischer (2003) said:The delicate balance of the rates of generation and deletion is responsible for the maintenance of a compact, clean genome and at the same time, allows the organism to efficiently explore the vast sequence space to generate diversity. The abundance of ORFans and PCOs is merely a consequence of this balance. Any change in the rate of generation/deletion may compromise survival. ORFans are simply the result of a natural evolutionary process and their number is exactly what would be expected from a scale-free system. Thus, in addition to the classical view of 'duplication with modification', the proposed model may be responsible for the enormous microbial diversity.
Aught3 said:Interesting ideas, would horizontal gene transfer count as a ORFan though? I thought it had to be a completely new gene which is why I mentioned de novo evolution.